Iphoyinti lokubilisa le-DMSO: Ukuhlaziywa Okubanzi kanye Nokuhlaziywa Kwesicelo
I-DMSO (i-Dimethyl Sulfoxide) iyi-solvent ye-polar organic esetshenziswa kabanzi kumakhemikhali, imithi, i-biotechnology nakweminye imikhakha. Kulesi sihloko, sizohlaziya izici zamaphuzu abilayo e-DMSO ngokuningiliziwe futhi sixoxe ngokusetshenziswa kwayo emikhakheni ehlukene.
Izakhiwo eziyisisekelo nendawo yokubilisa ye-DMSO
Ake sibheke izici eziyisisekelo ze-physicochemical ye-DMSO, okuwuketshezi olungenambala, olungenaphunga olunefomula yamakhemikhali ( \umbhalo{(CH}3)2\text{SO} ). Kuyaziwa nge-solvency yayo eyeqisayo kanye nobuthi obuphansi, ekwazi ukuhlakaza izinto eziningi ezipholile nezingezona i-polar, okuye kwaholela ekusetshenzisweni okubanzi emkhakheni wamakhemikhali kanye ne-biotechnological.
Iphuzu lokubilisa le-DMSO lingenye yezakhiwo zayo ezibaluleke kakhulu zomzimba. Ngokwedatha yokuhlola, indawo yokubilisa evamile ye-DMSO ingu-189°C. Leli phuzu lokubilisa eliphakeme uma kuqhathaniswa lisho ukuthi i-DMSO ihlala iwuketshezi ekamelweni lokushisa futhi ibonisa ukuzinza okuhle kokushisa ekusebenzeni okuphezulu kwezinga lokushisa. Lokhu kwenza i-DMSO ibe isinyibilikisi esibalulekile sokusabela kwamakhemikhali amaningi okushisa okuphezulu.
Umthelela wendawo yokubilisa ye-DMSO ezinhlelweni zokusebenza zezimboni
Iphuzu eliphezulu lokubilisa le-DMSO linomthelela omkhulu ezinhlelweni zayo zemboni. Ekuhlanganiseni kwamakhemikhali, indawo yokubilisa ingenye yezinto ezibalulekile ekukhetheni i-solvent, futhi indawo yokubilisa ye-DMSO engu-189 ° C isho ukuthi ihlala izinzile futhi ingaguquguquki emazingeni okushisa aphezulu, okuyinzuzo ekuphenduleni okuningi okudinga ukucutshungulwa kwezinga lokushisa eliphezulu. Isibonelo, ekuhlanganiseni kwezidakamizwa, i-DMSO ivame ukusetshenziselwa ukuncibilikisa ama-reactants futhi iqinisekise ukuthi ukusabela kwenzeka ezingeni lokushisa elilungile, kuyilapho igwema ukuhwamuka ngaphambi kwesikhathi kwe-solvent ngenxa yephuzu layo eliphezulu lokubilisa, elibuye lithuthukise ukusebenza kahle kokusabela kanye nesivuno somkhiqizo.
Iphuzu elibilayo le-DMSO liphinde linikeze inzuzo ku-distillation kanye nokuhlukanisa kanye nezinqubo zokuhlanza. Kulokhu, iphoyinti eliphezulu lokubilisa i-DMSO lingahwamuka ukuze kususwe ukungcola kwamaphuzu abilayo aphansi, ngaleyo ndlela kuthuthukiswe ukuhlanzeka. Lolu hlelo lokusebenza lutholakala kakhulu emikhakheni emihle yamakhemikhali neyokwenza imithi.
I-DMSO elabhorethri
I-DMSO iyisincibilikisi esingenakuthathelwa indawo ocwaningweni lwaselabhorethri ngenxa yezakhiwo zayo eziyingqayizivele.Iphuzu lokubilisa le-DMSO liyenza ifanelekele ukuhlola okuningi okudinga amazinga okushisa aphezulu, njengokusabela okuthile kwemvelo noma ukuhlolwa kokuncibilika emazingeni okushisa aphezulu. Izinyibilikisi ezisetshenziswa ngokujwayelekile elabhorethri, njenge-ethanol ne-ether, zinephuzu lokubilisa eliphansi kakhulu kune-DMSO futhi ngenxa yalokho azifaneleki ukuhlolwa okuthile kokushisa okuphezulu; Indawo yokubilisa ephezulu ye-DMSO iqinisekisa ukuthi ihlala imanzi emazingeni okushisa aphezulu futhi iqinisekisa ukuthi ukuhlolwa kwenziwa ngokushelela.
Ngenxa ye-biocompatibility yayo enhle kanye nephuzu eliphezulu lokubila, i-DMSO iphinde isetshenziswe ngokujwayelekile kubhayoloji yamaseli nokuhlolwa kwezidakamizwa njengesixazululi senkampani noma ekuncibilikiseni izidakamizwa okunzima ukuzixazulula. Inhlanganisela yephoyinti layo elibilisayo nokuncibilika kwenza i-DMSO isebenziseke ngokukhethekile kulo mkhakha.
Isifinyezo
Iphuzu elibilayo le-DMSO (189°C) lingenye yezinto zalo ezibonakalayo eziphawuleka kakhulu, ezingagcini nje ngokunquma ukusetshenziswa kwayo ekuphenduleni izinga lokushisa eliphezulu, kodwa futhi libe nomthelela ekusetshenzisweni kwayo kabanzi ekukhiqizeni izimboni kanye nocwaningo lwaselabhorethri. Ukuqonda ukubaluleka kwendawo yokubilisa ye-DMSO kusiza ukusebenzisa kangcono izici zayo ukuze kuthuthukiswe izimo zokusabela nokuthuthukisa imiphumela yokuhlola.
Ngokuhlaziya okungenhla, singabona ukubaluleka kanye nenani lokusetshenziswa kwephuzu elibilisayo le-DMSO, futhi ukuqonda okujulile kwezakhiwo zayo ezibonakalayo kuzosiza kakhulu ukuthuthukiswa okushelelayo komsebenzi ohlobene lapho kukhethwa futhi kusetshenziswa lesi sincibilikisi.